The preventive measures are necessary.
A, hepatitis B virus. Hepatitis B virus is second only to tobacco, the second known human carcinogen 5 - 90% of the causes of liver cancer
Xue factor, from a global perspective EfJ: l: infection and liver cancer distribution is consistent, of course, with the hepatitis B virus who are not necessarily the incidence or
The incidence is very light. But there are also some people into chronic persistent hepatitis, and cirrhosis. While most of liver cancer patients have different way
The evolution of hepatitis B from the history of cirrhosis, liver cancer and hepatitis B virus that is a causal relationship. Some people abroad that high
The infant hepatitis B vaccine program can reduce 80% of liver cancer patients, some scholars predict China will reduce about 70% of patients with liver cancer.
2, aflatoxin. Have a definite role in liver cancer caused by the strong will of all induced liver cancer in laboratory animals, is the human hepatoma
Before moving factor or promoting factor. My liver cancer is generally high incidence area of warm and humid, especially suitable for the growth of Aspergillus flavus. Have painted
Out of aflatoxin contamination of the distribution, and mortality of liver cancer is in good agreement with the geographic distribution. Aspergillus flavus is one of several toxic mold
Species its B1 on a strong liver toxicity, and hepatitis B virus were considered carcinogenic synergistic role. In addition, aflatoxin can get
Cellular immune function, hepatitis B virus to a certain crowd in high fashion, these will lead to some patients with persistent hepatitis B recover until
Development of cirrhosis or liver cancer. Preventive measures: mainly to prevent the grain, food mildew, especially vulnerable to focus on the moldy corn, peanuts
Aflatoxins, food monitoring, strict management of food hygiene, strict control of aflatoxin contamination of foodstuffs.
'3, Drinking water pollution. Investigation of hepatitis epidemic areas, drinking water quality is also seriously polluted areas. Epidemiological studies related
That, drinking ditch serious pollution, water (ponds) crowd cumulative incidence of hepatocellular carcinoma was significantly higher than that of well water to drink. HCC-high-incidence area
West county survey showed that: chemical mutagen in drinking water pollution and aflatoxin Bl intake to the level of the residents of liver cancer
Have a great impact on the rate of disease, there are synergies between the two carcinogenic effect. When the two factors coexist, residents of the high incidence of liver cancer income. Findings
Inspiration: If taken corresponding measures to reduce and eliminate water pollution, improve drinking water and reduce the incidence of hepatocellular carcinoma is possible.
4, Se. The selenium content in the blood is low-induced liver cancer may occur in the development of the condition factor. Research shows that:
Blood selenium levels and the incidence of hepatocellular carcinoma was negatively correlated with Se right spontaneous, and the transplantation of chemical or virus-induced cancer are paid for animals
Use can reduce the incidence of hepatocellular carcinoma 1 / 3 to 2 / 3. Selenium can improve immune function and detoxification function.
Five other factors. If genetic factors, high incidence of liver cancer families may be carcinogenic factor is the susceptibility; Nitrosamine carcinogen intake;
Alcohol liver damage; Hepatitis A, pesticides and parasitic diseases of the liver, these factors together constitute liver cancer incidence
The "dangerous state."
In conclusion, liver cancer prevention should be a "combat hepatitis, the good food to prevent mildew, selenium modest, improvement of drinking water" is the prevention of liver
Carcinoma of effective measures.
2008-08-03
China reports half of world's new liver cancer cases
BEIJING, July 28 (Xinhua) -- China has 350,000 new liver cancer patients every year, accounting for nearly half of the world's total, according to Leng Xisheng, president of the Chinese Collegeof Surgeons.
The deadly disease claims about 320,000 lives in the country each year, making it the third most common and second most deadly type of cancer, Leng told the launching ceremony of a new anti-cancer drug on Sunday.
Liver cancer has become the top killer in four provincial-level areas: Zhejiang, Jiangsu, Guangdong and Guangxi.
"The liver cancer incidence rate is still increasing in China," said Leng, who is also the director of Department of Hepatobiliary Surgery at Peking University People's Hospital.
Surgery and liver transplants can offer a cure at the early stages, but most cases are only detected in the intermediate or terminal stages, when life expectancy falls to four to six months on average, Leng said.
To extend late-stage patients' remaining survival time, the State Food and Drug Administration approved an oral drug, Nexavar, after it showed promise in clinical trials.
Editor: An Lu
The deadly disease claims about 320,000 lives in the country each year, making it the third most common and second most deadly type of cancer, Leng told the launching ceremony of a new anti-cancer drug on Sunday.
Liver cancer has become the top killer in four provincial-level areas: Zhejiang, Jiangsu, Guangdong and Guangxi.
"The liver cancer incidence rate is still increasing in China," said Leng, who is also the director of Department of Hepatobiliary Surgery at Peking University People's Hospital.
Surgery and liver transplants can offer a cure at the early stages, but most cases are only detected in the intermediate or terminal stages, when life expectancy falls to four to six months on average, Leng said.
To extend late-stage patients' remaining survival time, the State Food and Drug Administration approved an oral drug, Nexavar, after it showed promise in clinical trials.
Editor: An Lu
drinking coffee lowers liver cancer risk
BEIJING, June 27 (Xinhuanet) -- Coffee drinkers may be at less risk of liver cancer -- the third most common cause of cancer deaths worldwide -- based on a prospective population-based study that confirms an inverse relationship between coffee consumption and liver cancer risk.
The study also found that higher levels of gamma-glutamyltransferase (GGT) in the blood were associated with an increased risk of developing the disease.
Researchers led by Gang Hu at the University of Helsinki set out to examine the associations between coffee consumption and serum GGT with the risk of liver cancer in a large prospective cohort. Residents of Finland drink more coffee per capita than the Japanese, Americans, Italians, and other Europeans, so Hu and colleagues studied 60,323 Finnish participants ages 25 to 74 who were cancer-free at baseline. The Finns were included in seven independent cross-sectional population surveys conducted between 1972 and 2002 and followed up through June 2006.
The participants completed a mail-in questionnaire about their medical history, socioeconomic factors and dietary and lifestyle habits. For a subset of participants, clinical data was available, including serum levels of GGT. Data on subsequent cancer diagnoses was collected from the country-wide Finnish Cancer Registry.
Based on their answers to the question: "How many cups of coffee do you drink daily?" the participants were divided into five categories: 0-1 cup, 2-3 cups, 4-5 cups, 6-7 cups, and 8 or more cups per day. After a median follow-up period of 19.3 years, 128 participants were diagnosed with liver cancer.
The researchers noted a significant inverse association between coffee drinking and the risk of primary liver cancer. They found that the multivariable hazards ratio of liver cancer dropped for each group that drank more coffee. It fell from 1.00, to .66, to .44, to .38 to .32 respectively.
"The biological mechanisms behind the association of coffee consumption with the risk of liver cancer are not known," the authors point out.
They also found that high levels of serum GGT were associated with an increased risk of liver cancer. The hazard ratio of liver cancer for the highest vs. lowest quartile of serum GGT was 3.13. "Nevertheless," they report, "the inverse association between coffee consumption and the risk of liver cancer was consistent in the subjects at any level of serum GGT."
(Agencies)
The study also found that higher levels of gamma-glutamyltransferase (GGT) in the blood were associated with an increased risk of developing the disease.
Researchers led by Gang Hu at the University of Helsinki set out to examine the associations between coffee consumption and serum GGT with the risk of liver cancer in a large prospective cohort. Residents of Finland drink more coffee per capita than the Japanese, Americans, Italians, and other Europeans, so Hu and colleagues studied 60,323 Finnish participants ages 25 to 74 who were cancer-free at baseline. The Finns were included in seven independent cross-sectional population surveys conducted between 1972 and 2002 and followed up through June 2006.
The participants completed a mail-in questionnaire about their medical history, socioeconomic factors and dietary and lifestyle habits. For a subset of participants, clinical data was available, including serum levels of GGT. Data on subsequent cancer diagnoses was collected from the country-wide Finnish Cancer Registry.
Based on their answers to the question: "How many cups of coffee do you drink daily?" the participants were divided into five categories: 0-1 cup, 2-3 cups, 4-5 cups, 6-7 cups, and 8 or more cups per day. After a median follow-up period of 19.3 years, 128 participants were diagnosed with liver cancer.
The researchers noted a significant inverse association between coffee drinking and the risk of primary liver cancer. They found that the multivariable hazards ratio of liver cancer dropped for each group that drank more coffee. It fell from 1.00, to .66, to .44, to .38 to .32 respectively.
"The biological mechanisms behind the association of coffee consumption with the risk of liver cancer are not known," the authors point out.
They also found that high levels of serum GGT were associated with an increased risk of liver cancer. The hazard ratio of liver cancer for the highest vs. lowest quartile of serum GGT was 3.13. "Nevertheless," they report, "the inverse association between coffee consumption and the risk of liver cancer was consistent in the subjects at any level of serum GGT."
(Agencies)
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